Advanced Neurobiology I 

Welcome to Advanced Neurobilology!

1.1.1 Terminology

1.1.2 Central nervous system and blood brain barrier

1.1.3 Meninges

1.1.4 Telencephalon

1.1.5 The localization and globalization theory

1.1.6 White matter

1.1.7 Internal structures

1.1.8 Hippocampus and LTP

1.1.9 Cerebellum

1.2.1 Brain stem

1.2.2 Cranial nerves

1.2.3 Ascending and descending tracts and reticular formation

1.2.4 Pons

1.2.5 Reflex and reflex arc

1.2.6 Concepts in the CNS and PNS

1.2.7 Spinal cord

1.2.8 The visceral nervous system

1.2.9 Several pathways of the nervous system

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8 PET?fMRI

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Slides are available both in video and adneuro@outlook.com

Quiz 1.1

Quiz 1.2

Morphology of the neuronal cell & Cellular and Molecular Biology of the Neuron

2.1 Reductionism and hypothesis

2.2 Morphology of the neuron

2.3 Visualization of neurons and the neuron doctrine

2.4 The story of the fluorescent proteins

2.5 Stories of the Nobel prize

2.6 Organic fluorescent probes

2.7 Proteins specifically expressed in neurons and "brainbow" technique

2.8 Microscopy techniques I

2.9 Microscopy techniques II

2.10 The electron microscope

2.11 Glia and myelination

2.12 Research: AIS and Ankyrin G

3.1.1 A overview of neurons

3.1.2 Real life situation: A? in Alzheimer?s disease

3.1.3 Organelles and cytoskeleton in neurons

3.1.4 Research: induction of the tunneling nanotube

3.1.5 Defects in myelination and related diseases

3.1.6 Synthesis and trafficking of neuronal proteins I

3.1.7 Synthesis and trafficking of neuronal proteins II

Quiz 2

Quiz 3.1

Cellular and Molecular Biology of the Neuron

3.2.1 Cellular information transfer

3.2.2 Signaling molecules

3.2.3 Neurotransmitters and receptors

3.2.4 The synapse

3.2.5 Types of receptors

3.2.6 Crosstalk of cellular signal transduction pathways

3.2.7 The LTP

3.2.8 The molecular mechanism of learning and memory

3.2.9 Glia in a synapse

3.3.1 Alzheimer?s disease: introduction and myths

3.3.2 Alzheimer?s disease: pathology

3.3.3 Parkinson?s disease: introduction

3.3.4 Parkinson?s disease: symptoms and prognosis

3.3.5 Parkinson?s disease: pathology

3.3.6 Parkinson?s disease: treatment

3.3.7 Prion diseases

Quiz 3.2

Quiz 3.3

Signaling within neurons & Ion channels and membrane potentials

4.1 Overview

4.2 The resting potential

4.3 The resting potential and the Nernst equation

4.4 The Nernst Equation

4.5 Biological and electrical proporties of neurons I

4.6 Biological and electrical proporties of neurons II

4.7 Biological and electrical proporties of neurons III.

5.1 Ion channels and membrane potentials I

5.2 Ion channels and membrane potentials II

5.3 Ion channels and membrane potentials III

5.4 Ion channels and membrane potentials IV

5.5 Ion channels and membrane potentials V

5.6 Ion channels and membrane potentials VI

5.7 Ion channels and membrane potentials VII

5.8 Ion channels and membrane potentials VIII

Kang Shen - 1

Kang Shen - 2

Kang Shen -3

Kang Shen - 4

Kang Shen - 5

Kang Shen - 6

Kang Shen - 7

Kang Shen - 8

Liqun Luo - 1

Liqun Luo - 2

Liqun Luo - 3

Liqun Luo - 4

Liqun Luo - 5

Liqun Luo - 6

Liqun Luo - 7

Lab page of Dr. Kang Shen

Lab page of Dr. Liqun Luo

Quiz 4

Quiz 5

Ion channels, membrane potential and synaptic transmission

6.1 Voltage sensing

6.2 The Na+ gating current

6.3 Inactivation gates

6.4 Ion channel, membrane potential and synaptic transmission I

6.5 Ion channel, membrane potential and synaptic transmission II

6.6 Ion channel, membrane potential and synaptic transmission III

6.7 Ion channel, membrane potential and synaptic transmission IV

6.8 Ion channel, membrane potential and synaptic transmission V

Quiz 6

Neurotransmitter release

7.1 How does Ca2+ control neurotransmitter release I

7.2 How does Ca2+ control neurotransmitter release II

7.3 How does Ca2+ control neurotransmitter release III

7.4 How does Ca2+ control neurotransmitter release IV

7.5 Molecular mechanism involved in neurotransmetter release I

7.6 Molecular mechanism involved in neurotransmetter release II

7.7 Molecular mechanism involved in neurotransmetter release III

7.8 Molecular mechanism involved in neurotransmetter release IV

7.9 Molecular mechanism involved in neurotransmetter release V

7.10 Molecular mechanism involved in neurotransmetter release VI

7.11 Molecular mechanism involved in neurotransmetter release VII

7.12 Molecular mechanism involved in neurotransmetter release VIII

7.13 Molecular mechanism involved in neurotransmetter release IX

7.14 Molecular mechanism involved in neurotransmetter release X

Quiz 7

Synaptic transmission & Synapitic plasticity

8.1 Synaptic trasmission I

8.2 Synaptic trasmission II

8.3 Synaptic trasmission III

8.4 Synaptic transmission IV

8.5 Synaptic trasmission V

8.6 Synaptic trasmission VI

9.1 Synapitic plasticity I

9.2 Synapitic plasticity II

9.3 Synapitic plasticity III

9.4 Synapitic plasticity IV

9.5 Synapitic plasticity V

9.6 Synapitic plasticity VI

Quiz 8

Quiz 9

Techniques in neuroscience

10.1 Observation and perturbation

10.2 Animal models in neurological research

10.3 Genetic and molecular techniques

10.4 Anatomical techniques

10.5 Mapping synaptic connections

10.6 Patch recording and optical imaging

Quiz 10