Rice University - Fundamentals of Immunology: Innate Immunity and B-Cell Function
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- Public/Government Institute
Fundamentals of Immunology: Innate Immunity and B-Cell Function at Coursera Overview
Duration | 16 hours |
Total fee | Free |
Mode of learning | Online |
Difficulty level | Intermediate |
Official Website | Explore Free Course  |
Credential | Certificate |
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Fundamentals of Immunology: Innate Immunity and B-Cell Function at Coursera Highlights
- Shareable Certificate Earn a Certificate upon completion
- 100% online Start instantly and learn at your own schedule.
- Course 1 of 4 in the Fundamentals of Immunology Specialization
- Flexible deadlines Reset deadlines in accordance to your schedule.
- Intermediate Level
- Approx. 16 hours to complete
- English Subtitles: Arabic, French, Portuguese (European), Italian, Vietnamese, German, Russian, English, Spanish
Fundamentals of Immunology: Innate Immunity and B-Cell Function at Coursera Course details
- Course 1 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material.
- This is the first leg of a three-part journey through the defenses your body uses to keep you healthy. In this part we hope to give you the vocabulary and concepts you need to interact with the medical community and to provide them in a context that makes them memorable.
- Fundamentals of Immunology introduces students to the basic functions of the adaptive and innate immune systems. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. After describing the form, function, origin and varieties of antibodies, subsequent lectures provide details on the mechanism of the generation of variation. The course provides animations of gene rearrangement and class switching and descriptions of affinity maturation correlated with detailed physical models of antibody structure. The final lecture reviews these concepts in anatomical context. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline.
- What You'll Learn:
- The difference between adaptive and innate immune systems, the characteristics of various pathogens that they protect you from and the overall strategies employed in this protection. The detailed structure of antibodies and related immunoglobulin receptors, the characteristics and function of the different antibody classes and the mechanism for producing both the recognition regions and stem regions. Finally, how these structures are coded for in the DNA and expressed in the B cells.
Fundamentals of Immunology: Innate Immunity and B-Cell Function at Coursera Curriculum
Introducing the Metaphors
Welcome
Staying Healthy
Pathogen Varieties
Pathogen Recognition
Words of Advice
Metaphors of Power Politics
Innate Versus Defensive Responses
Grading Information
Course Study Guide
Pre-Course Survey
Lesson 2 Questions
Lesson 3 Questions
Lesson 4 Questions
Lesson 5 Questions
Lesson 6 Questions
Lesson 7 Questions
Lecture 1 Practice Quiz
Lecture 1 Quiz
Surveying the Cells and Organs of the Immune System
Terminology
Hematopoiesis
Myeloid Granulocytes
Myleolid Antigen Presenting Cells
Lymphocytes
Primary Organs
Lymph: Fluid, Vessels and Nodes
Other Secondary and Tertiary Organs
Final Issues
Lesson 1 Questions
Lesson 2 Questions
Lesson 3 Questions
Lesson 4 Questions
Lesson 5 Questions
Lesson 6 Questions
Lesson 7 Questions
Lesson 8 Questions
Lesson 9 Questions
Practice Quiz 2
Quiz 2
Innate Immunity
Basic Considerations
Inflammation
Innate Targeting of Pathogens
Myeloid Cell Function
Innate and Adaptive Immunity Compared
Lesson 1 Questions
Lesson 2 Questions
Lesson 3 Questions
Lesson 4 Questions
Practice Quiz 3
Quiz 3
Antigens and Antibodies
Context
The Immunoglobulin Superfamily
Ig Receptors and Antibodies
Form and Function
Immunoglobulin Classes
Specific Ig Types
Immunoglobulins in Action
Fc Biological Activity
The B Cell Receptor
Monoclonal Antibodies
Lesson 1 Questions
Lesson 2 Questions
Lesson 3 Questions
Lesson 4 Questions
Lesson 5 Questions
Lesson 6 Questions
Lesson 7 Questions
Lesson 8 Questions
Lesson 9 Questions
Lesson 10 Questions
Practice Quiz 4
Quiz 4
Immuniglobulin Genes
Uniqueness of the System
Scales and Models
Gene to RNA to Protein
Light Chain Gene Expression
Heavy Chain Gene Expression
Rearrangement in Developmental Context
Recombination Signal Sequence Structure
Mechanism Details
Commitment to a Definite CDR
Generation of Antibody Diversity
Class Switching
Synthesis and Secretion
Lesson 1 Questions
Lesson 2 Questions
Lesson 3 Questions
Lesson 4 Questions
Lesson 5 Questions
Lesson 6 Questions
Lesson 7 Questions
Lesson 8 Questions
Lesson 9 Questions
Lesson 10 Questions
Lesson 11 Questions
Practice Quiz 5
Quiz 5
Development of B Cells
B Cell Maturation
Initial Steps in Bone Marrow
Activation: Thymus Independent
Primary and Secondary Responses: T Cells
Anatomical and Histological Context
Affinity Maturation
Final Decisions
Regulation
Lesson 1 Questions
Lesson 2 Questions
Lesson 3 Questions
Lesson 4 Questions
Lesson 5 Questions
Lesson 6 Questions
Lesson 7 Questions
Lesson 8 Questions
Practice Quiz 6
Quiz 6
Farewell
End-of-Course Survey
Final
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