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SGUL - Interpreting Genomic Variation: Inherited Cancer Susceptibility 

  • Offered byFutureLearn

Interpreting Genomic Variation: Inherited Cancer Susceptibility
 at 
FutureLearn 
Overview

Duration

2 weeks

Total fee

8,364

Mode of learning

Online

Credential

Certificate

Interpreting Genomic Variation: Inherited Cancer Susceptibility
Table of content
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  • Overview
  • Highlights
  • Course Details
  • Curriculum

Interpreting Genomic Variation: Inherited Cancer Susceptibility
 at 
FutureLearn 
Highlights

  • Earn a certificate of completion from Futurelearn
Details Icon

Interpreting Genomic Variation: Inherited Cancer Susceptibility
 at 
FutureLearn 
Course details

More about this course
  • On this course, you will consider how variant interpretation in cancer susceptibility genes has different considerations when compared with variant interpretation in rare paediatric disease
  • You'll explore the guidelines produced by the UK Cancer Variant Interpretation Group (CanVIG-UK) for variant interpretation and how these can be applied to the American College of Medical Genetics (ACMG) framework in the classification of germline variants in cancer susceptibility genes
  • This course will provide you with patient examples to explore the complexities of variant interpretation in cancer genomics
  • You'll also hear from experts in the field about how the CanVIG-UK guidance was created
  • You'll be encouraged to apply your learning through case-based exercises that illustrate both the strengths and weaknesses of the tools and guidelines available for cancer variant interpretation
Read more

Interpreting Genomic Variation: Inherited Cancer Susceptibility
 at 
FutureLearn 
Curriculum

Cancer susceptibility gene variant interpretation

Introduction to the course

Why is variant interpretation different in Cancer Susceptibility Genes (CSGs)?

Adapting the ACMG framework for CSGs

Population data

Computational and predictive data

Cancer susceptibility gene variant interpretation

Introduction to Week 2

Functional data

Allelic data

Reputable sources

Other data

Other considerations

Pulling it all together

Putting it into practice

The evolving landscape

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Interpreting Genomic Variation: Inherited Cancer Susceptibility
 at 
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