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Signaling actions of small molecules 

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Signaling actions of small molecules
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Overview

Duration

10 hours

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Free

Mode of learning

Online

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Certificate

Signaling actions of small molecules
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Coursera 
Highlights

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  • 7 quizzes
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Signaling actions of small molecules
 at 
Coursera 
Course details

What are the course deliverables?
  • What you'll learn
  • Learn about fundamental principles underlying various cellular signaling events controlled by endogenous small molecules
More about this course
  • Our life is fine-controlled by various molecules in cells. Different types of molecules include macromolecules (e.g., protein, nucleic acid) and small molecules. In addition to classical views of central dogma, emerging roles of small molecules called metaboites have been recently proposed to significantly impact biological events. Metabolites are contiuously and dynamically produced by different metabolic pathways, thus playing key roles in energy metabolism as well as macromolecular biosynthesis/degradation. Accumulating evidence clearly suggests that certain types of metabolites exert signaling actions through interactions with macromolecules. Compared to other protein-protein and nucleic acid-protein interactions, metabolite-protein interactions appear significant in living cells, therby mediating specific actions in regulating target protein functions and activities.
  • This 6 week-course will give you a solid introduction to the basic fundamentals of metabolite-mediated cell signaling. I will first define the concept of metabolites and introduces major types of molceular interactions. Throughout 6 weeks, we will study biochemical basis of metabolite actions in cell signaling. In particular, we will study interesting examples of how endogenous small molecules intreact with target proteins and control their functions. These major topics will be explained in the context of human health and disease such as cancer and inflammtion. Everyone appreciates that cell signaling is essential for sustaining life. How can you explain the action of noxious gases like nitric oxide in controlling blood pressure? What can be the fundamental mode of energy metabolites in modulating gene expression? Have you ever thought about ways of how our gut microbiota can influence our body? By studying signaling actions of metabolites, we can better understand the complex but wonderful nature of our cellular signaling system, further identifying novel ways to manage major human disease.
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Signaling actions of small molecules
 at 
Coursera 
Curriculum

Week 1

Week 1 Introduction

1-1

1-2

1-3

1-4

1-5

Week 1 Lecture Note

New Quiz

Week 2

Week 2 Introduction

2-1

2-2

2-3

2-4

2-5

Week 2 Lecture Note

Quiz 2

Week 3

Week 3 Introduction

3-1

3-2

3-3

3-4

3-5

Week 3 Lecture Note

Quiz 3

Week 4

Week 4 Introduction

4-1

4-2

4-3

4-4

4-5

Week 4 Lecture Note

Quiz 4

Week 5

Week 5 Introduction

5-1

5-2

5-3

5-4

5-5

Week 5 Lecture Note

Quiz 5

Week 6

Week 6 Introduction

6-1

6-2

6-3

6-4

6-5

Week 6 Lecture Note

Quiz 6

Final exam

Signaling actions of small molecules
 at 
Coursera 
Admission Process

    Important Dates

    May 25, 2024
    Course Commencement Date

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    Signaling actions of small molecules
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