CBSE 10th

For getting into IIM, first you need to attend for PI/What rounds conducted by IIM's. For getting a call from reputed IIM's you must possess a good percentile in CAT exam. Good percentile could be at-least more than 90 for general category.
These play a major role in getting a call from IIM. An average scholar with at least an aggregate of 85% in X, XII and 65% in UG can get a chance to get into IIM.
One should be able to speak fluently in English, which helps to defeat the others in GD (in some cases) and it also helps in PI as well. Because one needs to understand what the interviewer is asking and able to communicate his/her views clearly. Next comes to writing, where in you need to write an essay on the topic given. For mastering in that round, you should know the correct grammar usage and good comprehension.
Moreover, for a successful conversation of an IIM call, it is depends on your abilities too like convincing skills, answering skills, etc. Also, there may be many factors such as work experience, academic achievements, etc., which do not count for minimum requirement for getting into IIM but if you do possess them, they tend to an added advantage.

There are 20 functional IIMs right now in the country. Every year each of them releases their criteria for calling students for GD/WAT/PI rounds. Though academic performance at school does make an impact on a student's chances of getting a call from the IIMs, it is to be kept in mind that it's not the only criteria. One can always make up in other areas like CAT percentile, UG percentage or work experience. As far as weight-age is considered, different IIMs weigh the scores differently while calculating their composite scores for the selection process. Since you are still in the first year of your under graduation, try to score as high as you can in the same and later in the CAT.
Since the criteria are subject to change every year, it's difficult to answer what percentage will be required in the year you appear for CAT.

Selection of the graduate courses ( BE / B.Tech ) is based on merit i.e the marks secured in the final exams of 10+2 and through entrance exams. Entrance to the IIT's is through JEE (Joint Entrance Exam) and for other institutions through their own separate entrance exams and other state level and national level exams. Apart from the IIT's, some other famous institutes also recognize JEE scores for selection.
Currently, students do not have much choice when it comes to genetic engineering colleges. Please use the link provided below for a list of colleges which offer genetic engineering courses in India.
https://www.shiksha.com/engineering/colleges/genetic-engineering-colleges-india