B.E.

Yes, this is possible because,
1. Candidates must hold a Bachelor's Degree or equivalent qualification of any of the Universities incorporated by an act of the central or state legislatures in India or other educational institutions established by an act of Parliament or declared to be deemed as a University under section 3 of UGC Act, 1956, or possess an equivalent qualification recognized by the Ministry of HRD, Government of India/AIU. This degree must entail a minimum of three years of education (10+2+3 system) after completing higher secondary schooling (Class 12 or equivalent).
2. Candidates of B.Sc / BA Honours must have minimum 55% marks in average (45% for SC/ST) in their Honors subject. Candidates of other graduate courses must have minimum 55% marks in average (45% for SC/ST) in graduation, marks to be computed as average of marks obtained in ALL subjects in which candidate has appeared (excluding optional subjects). I think you know about. P. J. Abdul Kalam the University of Madras, from where he graduated in physics in 1954. Towards the end of the course, he was not enthusiastic about the subject and would later regret the four years he studied it. He then moved to Madras in 1955 to study aerospace engineering.
Thank you.