CBSE 12th

Hi Varsha,
Arts and Humanities seems to be the obvious choice. Here is a link which should help both of you to map her real talents for the most suitable course:
https://www.shiksha.com/careers/opportunities

Hi Himanshi,
NIOS is a recognized body and is accepted everywhere. You are eligible to apply to DU. But every college has its own eligibility criteria for a particular program, you have to check the college websites for the requirements before applying.

Hello Chirag,
Yes, that is true that you need to have 75% in boards, but that is only the case with JEE Mains paper 2. All the JEE exams require a 75% in board exams for admission into NITs and the other colleges that come under JEE.
Even for JEE Mains paper 1 (B.Tech), you need to have 75% in HSC to get an NIT even if you have scored 300/360.
In case of NATA exam (National Aptitude Test in Architecture), it is enough to have 50% in mathematics and English. These are compulsory subjects and you should have passed the exam with 50%.

Hi Madhu,
Please consider NIOS and Andhra Pradesh Open School Society. Chances are minimal of pursuing both polytechnic and class 12th together even though you choose open schooling. It is best you confirm with the schools for any provisions.

Hi Vaishnavi,
Applicants must have a minimum of 75% (65% for SC/ST/PWD) marks in aggregate in maths and science subjects (Physics/Chemistry/Biology) in class 10th board exams and a minimum of 60% (50% for SC/ST/PWD) marks in aggregate in maths and science subjects (Physics/Chemistry/Biology) in the class 12th board exams . For details and updates please visit the KVPY website.
http://kvpy.iisc.ernet.in/main/eligibility.htm

Professional courses are better than normal B.Sc.
You can do B.Sc in nursing.
BPT (Bachelor of Physiotherapy). There are many other good courses if you have an interest in the medical field.

Hi Sipun,
There could be many options from engineering to management, but the decision has to be made solely on your own interests and career plans. You must know what you enjoy and eventually succeed. I will suggest that you take help of this career counselling page and map your interests to the most suitable talent.
https://www.shiksha.com/careers/opportunities
All the best for your future.

Hi Annie,
In order to facilitate Shiksha experts to give you accurate and precise answers, it is important that you give us a little more information regarding the subject you are currently studying (stream: Arts, Science or Commerce) as well as your interests. Once you share this with us, our experts will be able to help you out better.

Hi Aman,
Yes, you may. Different colleges under DU have different cut-off lists which have not been announced yet. For an idea, you can check previous year's cut-offs and merit lists. Please visit DU university official website for updates. For previous year cut-offs, you can also refer to this article below:
https://www.shiksha.com/humanities-social-sciences/articles/du-cut-off-trends-for-past-years-blogId-12697