B.Tech

Based on what you've shared:

MHT CET PCB: 89.5 percentile 

MHT CET PCM: 61 percentile 

You are interested in both Biotechnology/Bioinformatics and CSE/IT/AI-ML.

My recommendation

I would suggest you choose B.Tech Biotechnology or Bioinformatics rather than taking CSE/IT/AI-ML in a low-tier college.

Here's why:

With 61 percentile in PCM, getting a good CSE/IT/AI-ML seat through MHT CET is difficult. You may have to settle for a lower-ranked college, where placements are often limited. Top engineering colleges generally require much higher percentiles for CSE-related branches. 

With 89.5 percentile in PCB, you have a much better chance of getting into a good Biotechnology or Bioinformatics program. 

Career opportunities

If you choose Biotechnology/Bioinformatics:

Bioinformatics Scientist

Genomics Analyst

Clinical Data Analyst

Pharmaceutical Research

Drug Discovery

AI in Healthcare

Higher studies (M.Tech/MS/PhD) in India or abroad

If you choose CSE:

Choose it only if you are getting it in a reputed college. A strong college and learning environment matter a lot in software careers.

If you are equally interested in both

Bioinformatics is a great middle ground because it combines:

Biology

Programming

Artificial Intelligence

Data Science

If you enjoy both biology and coding, Bioinformatics can give you opportunities in healthcare technology, genomics, and AI-driven medical research.

Good colleges you can consider

With your PCB percentile, you should explore:

SASTRA University (Bioinformatics)

MIT World Peace University (Biotechnology)

DY Patil University (Biotechnology)

Symbiosis School of Biological Sciences

Other Maharashtra colleges offering Biotechnology/Bioinformatics through MHT CET or institute-level admissions.

Final advice

Since your PCM percentile (61) is much lower than your PCB percentile (89.5), I would not recommend joining a low-tier CSE college just for the branch name. A good Biotechnology/Bioinformatics programme from a better institution is likely to provide stronger long-term opportunities, especially if you're open to higher studies or interdisciplinary careers.

If you have to choose only between Chitkara University and Chandigarh University for B.Tech CSE, I would recommend Chandigarh University (CU) for most students.

Comparison

Factor

Chandigarh University

Chitkara University

Placements

⭐ Better overall, especially for CSE

Good, but slightly behind CU overall

Industry tie-ups

Very strong

Strong

Coding culture

Better due to a larger student community and more hackathons

Good

Campus & infrastructure

Excellent

Excellent

Fees

Similar

Similar

Chandigarh University generally has:

A larger number of IT recruiters.

Better exposure through hackathons, internships, and industry collaborations.

Strong placement opportunities for CSE students, with companies such as Microsoft, Amazon, IBM, Deloitte, Cognizant, Infosys, and Wipro visiting the campus. 

Chitkara University is also a good choice and has:

NAAC A+ accreditation.

Good industry partnerships.

Strong placement support with recruiters including Amazon, Microsoft, Deloitte, Infosys, Cognizant, and HCL. 

My recommendation

✅ Choose Chandigarh University if your priority is placements, industry exposure, and career opportunities.

✅ Choose Chitkara University if you prefer a comparatively more structured and disciplined academic environment.

Yes, you have a realistic chance of getting B.Tech Bioinformatics at SASTRA University with your ranks:

AIR: 13,999

Tamil Nadu Rank (TNR): 4,484

Bioinformatics is not one of the highest-demand branches like CSE or AI, so its cutoff is generally more relaxed. In the current admission cycle, SASTRA has continued to offer Bioinformatics seats in later counselling rounds, indicating that seats remain available after the initial rounds. 

Based on previous admission trends, your chances are:

B.Tech Bioinformatics: ✅ Good chance

B.Tech Biotechnology: ✅ Good chance

Bioengineering: ✅ Very good chance

There is no guarantee until the official allotment is released, but your ranks are competitive for Bioinformatics, especially if you have filled it as one of your higher preferences and participate in all counselling/sliding rounds.