IISER Bhopal Scientists identify circular RNA to help HIV treatment
This breakthrough research reveals how ‘ciTRAN,’ a circular RNA molecule, influences the virus's transcription process, which could potentially lead to novel therapeutic strategies against HIV-1
A team of researchers at IISER Bhopal has identified a circular RNA molecule, named ‘ciTRAN’, which plays a significant role in replication of the HIV-1 virus.
Circular RNAs differ from typical linear RNAs because they form a closed-loop structure. Although they are naturally present in very small amounts inside cells, they have been found to regulate gene expression in several contexts. Understanding their role during viral infections, however, has been challenging.
Dr. Ajit Chande, who led the study, said that circular RNAs are “much harder to detect because they appear in lower quantities and often get overshadowed by the large amount of viral RNA during infections.”
Team found that HIV-1 makes use of this host-derived circRNA to support its own transcription process, effectively helping the virus multiply more efficiently. “Our results indicate that the HIV-1 virus hijacks this host-encoded ciTRAN in such a way that it can use it to multiply efficiently,” Dr. Chande said.
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Abhay Anand is an experienced education journalist with over 15 years in print and digital media. Currently serving as Manager- Editorial at Shiksha.com, he specializes in higher education policy, student mobility,
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Student Forum
Anything you would want to ask experts?Answered 5 months ago
IISER Bhopal isn't the place for a typical B.Tech in Computer Science or Electrical. They're more into pure sciences and research stuff. You'll find BS-MS dual degrees, a BS in Engineering Sciences, and integrated PhD programs there—not the regular engineering tracks. If you're aiming for a classic
S
Contributor-Level 9
Answered 4 months ago
That's a great question, and it's wonderful that you're still exploring opportunities with IISER! However, for admission to the IISERs (Indian Institutes of Science Education and Research), there is a specific eligibility criterion regarding the year of passing your 12th standard. The admission crit
A
Contributor-Level 9
Answered 5 months ago
No, the Indian Institutes of Science Education and Research (IISER) do not offer standalone B.Sc. programs. Instead, they provide integrated BS-MS programs that combine undergraduate and postgraduate studies over five years. These programs emphasize research-oriented learning in disciplines like bio
A
Contributor-Level 9
Answered 5 months ago
If you are a biology student you must have pcb as your subjects but the B.Tech at IISER bhopal or at any college in India does require maths as a compulsory subject
In case you have pcmb you are totally eligible but not with PCB
thank you
D
Contributor-Level 9
Answered 5 months ago
IISER Bhopal cutoff 2025 for admission to the BS + MS course across multiple specialisations was 2015 for the students belonging to the General AI quota. For BTech admission, the cutoff rank stood at 974 for different specialisations. This is the cutoff rank for Round 1. Please note that the cutoff
R
Contributor-Level 10
Answered 5 months ago
IISER Bhopal cutoff 2025 has been released for different categories of students under the AI quota. For the General category, the cutoff rank for BS + MS admission across multiple specialisations was 2015. For BTech, the Round 1 closing rank stood at 974. To view the category-wise ranks, refer to th
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Contributor-Level 10
Answered 6 months ago
IISER Bhopal cutoff 2025 has been released for admission to MSc specialisations. The cutoff was released for M.Sc. in Mathematics, M.Sc. in Chemistry and M.Sc. in BioTechnology. Given below are the cutoff branch-wise ranks for the General AI category candidates:
| Course | 2025 |
|---|---|
| M.Sc. in Mathematics | 610 |
| M.Sc. in Chemistry | 699 |
| M.Sc. in BioTechnology | 89 |
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Contributor-Level 6
Answered 7 months ago
IISER Bhopal mein B.Tech in Engineering and Computational Sciences (ECS) ke liye admission lene ke liye aapko JEE Advanced clear karna hota hai. EWS category ke liye cut-off thoda relaxed hota hai, lekin general estimate ke hisaab se aapko JEE Advanced mein around 55–70 marks ya uske aaspaas score k
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Contributor-Level 10
IISER Bhopal is one of the best options to pursue BSc. It has great faculty that is always there to guide students. Infrasturcture at the college is great, with state of the art laboratories, a library with large collecion of books on different subjects. Students and especially, seniors are really great when it comes to proper guidance. IISER Bhopal has connections to most of the big research firms, helping students to secure good internships and placement.