Important Topics of Biology for IISER Entrance Exam 2025; Check Topics and Subject Weightage

Indian Institutes of Science Education and Research Entrance Exam 2026 ( IISER Entrance Exam )

DeskCalelnderRegistration - 5 Mar '26 - 13 Apr '26

Manisha
Manisha Kumari
Associate Senior Executive
Updated on Apr 30, 2025 14:45 IST
IISER Exam 2025 Biology sections comprise 15 questions and exam officials test candidates' domain knowledge and analytical understanding of the Class 11 and 12 Biology syllabus. Check out this Shiksha article to know the IISER exam 2025 important topics of biology to ace the exam with an extra score.

IISER Exam 2025 Biology sections comprise 15 questions, and exam officials test students' domain knowledge and analytical understanding of the Class 11 and 12 Biology syllabus. Check out this Shiksha article to know the IISER exam 2025 important topics of biology to ace the exam with an extra score.

Biology Important Topics  For  IISER Entrance Exam

Biology Important Topics For IISER Entrance Exam

The Indian Institutes of Science Education and Research (IISER) offer one of the most prestigious science education programs in India. The IAT is conducted annually for admission into the BS-MS dual degree programs. Among the four subjects tested—Physics, Chemistry, Mathematics, and Biology—many students find Biology either their strongest or weakest link. Regarding the high competition level of the examination, a strategic IISER Biology Preparation must be done by the test takers.

Also Read: IISER 2025 New Changes Introduced: Eligibility (Reinstated), New Courses, Seat Intake & Other Details

Table of contents
  • IISER Entrance Exam Overview and Biology Weightage
  • Most Important Topics in Biology for IAT 2025
  • IAT 2025: Biology Topic-Wise Weightage
  • IISER Entrance Exam 2025: Preparation Strategy for Biology
  • Last-Minute Tips for Biology in IAT 2025
  • How to Attempt the Biology Section in the exam

IISER Entrance Exam Overview and Biology Weightage

The IISER Entrance Exam consists of 60 multiple-choice questions, 15 from every subject. The paper is distributed equally among the four core subjects:

  • Biology – 15 Questions

  • Physics – 15 Questions

  • Chemistry – 15 Questions

  • Mathematics – 15 Questions

Each question carries 3 marks, and 1 mark is deducted for incorrect answers. Hence, a good performance in Biology can significantly boost your overall score.

Also Read: IISER Biology Syllabus 2025 (OUT): Check Class 11 and Class 12 NCERT Biology Syllabus Here 

Q&A Icon
Commonly asked questions
Q:   When will the first round of admissions start for the IISER entrance exam?
A: 

Once IISER result is declared, a seat allotment list is declared containing roll numbers of candidates who are allocated seats in BS-MS programmes. Candidates can check the first round allotment list on the official website of the exam tentatively by the second week of July 2026. All candidates whose roll numbers appear in the first round allotment list need to log in to their application portal to download the offer letters.

Q:   When will be the Portal open to upload documents and freeze IISER preferences for IISER 2026 Admissions?
A: 

The portal for document upload and freezing of IISER preferences for IISER 2026 Admissions is expected to begin in the month of July 2026, tentatively. After accepting the offer and paying the seat acceptance fee, the candidate can exercise two options:

  1. Candidate can FREEZE the seat (they will not participate in further rounds of counselling),
  2. Candidate can FLOAT (they will participate in further rounds of counselling to get their higher preferences). The FLOAT option is activated by default for those who pay the seat acceptance fee. A student who has chosen to FLOAT will again be considered for seat allocation in the next round. If they are eligible to secure a seat in an IISER that is higher in their preference list than the currently accepted one, they will be offered that seat.

Most Important Topics in Biology for IAT 2025

Cell Structure and Function:

Key Topics:

  • Cell theory

  • Prokaryotic vs eukaryotic cells

  • Cell organelles: structure and function

  • Biomolecules

  • Cell division: Mitosis and Meiosis

Why it's important: This chapter is heavily conceptual and frequently tested. Questions often revolve around organelle functions and phases of cell division.

Tip: Focus on diagrams and differences (e.g., between prokaryotic and eukaryotic cells, or mitosis vs meiosis).

Genetics and Evolution:

Key Topics:

  • Mendel’s laws of inheritance

  • Dihybrid and monohybrid crosses

  • Sex determination

  • DNA structure, replication, and transcription

  • Genetic disorders

  • Evolutionary theories

Why it's important: This is a high-yield topic. IAT frequently includes tricky questions involving Punnett squares or pedigree charts.

Tip: Practice lots of genetics problems. Understanding inheritance patterns and calculations is essential.

Human Physiology:

Main Points:

  • Digestive system

  • Respiratory system

  • Circulatory system

  • Excretory system

  • Nervous and muscular system

  • Endocrine glands

Why it's important: At least 2–3 questions are expected from this section. Diagrams and function-based questions are common.

Tip: Use flowcharts and summary tables to remember hormone actions and feedback mechanisms.

Plant Physiology:

Main Topics:

  • Photosynthesis

  • Respiration in plants

  • Transport in plants

  • Plant hormones

  • Growth and development

Why it's important: This area is rich in conceptual understanding and processes. Numerical and factual questions based on diagrams and reactions are common.

Tip: Focus on light and dark reactions, and functions of plant hormones (like auxins, gibberellins, etc.).

Ecology and Environment:

Important Topics:

  • Ecosystems

  • Biodiversity and conservation

  • Environmental issues

  • Organisms and populations

  • Biogeochemical cycles

Why it's important: This is often considered easier and scoring. Questions are usually direct and based on facts.

Tip: Focus on understanding the food chains, ecological pyramids, and biogeochemical cycles.

Reproduction:

Main Topics:

  • Reproduction in organisms

  • Sexual reproduction in flowering plants

  • Human reproductive system

  • Reproductive health

  • Gametogenesis and fertilisation

Why it's important: Diagrams, hormonal control, and stages of development are frequently asked.

Tip: Understand the menstrual cycle, gametogenesis, and male/female reproductive structures clearly.

Biotechnology and Its Applications:

Key Topics:

  • Principles of biotechnology

  • Genetic engineering (rDNA technology)

  • Applications in health and agriculture

  • Genetically Modified Organisms (GMOs)

Why it's important: This is a modern and application-based topic. It can have 1–2 questions in IAT.

Tip: Focus on the steps in gene cloning, the use of restriction enzymes, and practical applications like Bt cotton.

Also Read:

IISER Physics Syllabus IISER Mathematics Syllabus
IISER Biology Syllabus IISER Chemistry Syllabus
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IAT 2025: Biology Topic-Wise Weightage 

Based on analysis of past papers and trends:

Topic Approximate Weightage
Cell Structure & Function 2–3 Questions
Genetics and Evolution 2–3 Questions
Human Physiology 2–3 Questions
Plant Physiology 1–2 Questions
Ecology and Environment 1–2 Questions
Reproduction 1–2 Questions
Biotechnology 1 Question
Diversity & Classification 1 Question

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IISER Entrance Exam 2025: Preparation Strategy for Biology

1. Follow NCERT Thoroughly

Most IAT Biology questions are directly or indirectly based on the NCERT. Do not skip:

  • Line-by-line reading

  • Diagrams and tables

  • NCERT summary boxes

2. Practice with PYQs

Solving IISER previous year question papers (PYQs) helps you know the type of questions and difficulty level.

3.  Make Topic-Wise Notes

Summarise each chapter with:

  • Key terms

  • Diagrams

  • Important points

  • Mnemonics for classification or steps

4. Revise Regularly

Biology involves a lot of memorisation. Use spaced repetition techniques and flashcards for regular revision.

5. Practice papers 

Simulate the exam environment with full-length IAT practice papers. Analyse your performance in the Biology section to identify weak areas.

6. Recommended Resources

Books:

  • NCERT Class 11 & 12 Biology – Primary resource

  • Trueman’s Elementary Biology Vol I & II – For deeper understanding

  • MTG Objective NCERT at Your Fingertips (Biology) – For practice questions

Also Read: IISER Entrance Exam 2025 Books: Check Best Books for Exam Preparation 

Last-Minute Tips for Biology in IAT 2025

  • Quickly revise key concepts and flowcharts

  • Focus on high-yield topics like Genetics, Cell Biology, and Human Physiology

  • Solve 2–3 mock papers weekly in the last month

  • Stay updated with any syllabus changes from the official IISER site

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How to Attempt the Biology Section in the exam

  • Start with direct questions like Ecology or Reproduction to gain confidence

  • Mark doubtful questions for review and come back later

  • Avoid guesswork—each incorrect answer reduces your net score

  • Use elimination to improve your odds on tricky MCQs

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About the Author
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Manisha Kumari
Associate Senior Executive
Being a post-graduate and BEd degree holder, I'm an innovative, task-driven and immensely motivated science enthusiast, making me a passionate content writer. I love providing meaningful and constructive articles in Read Full Bio
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Answered 6 days ago

IISER score 200 or above is a good marks. It can help to get admission to IISER Pune and IISc Bangalore. Candidates must have a good conceptual knowledge, give priority to all four subjects. Prepare for the exam according to the exam syllabus and take mock test to score above 200.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 6 days ago

Based on previous year analysis, IAT exam is moderately difficult. It requires strong conceptual knowledge. Students who have prepared properly for exam can easily score good marks.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered a week ago

It is quite difficult for the GEN / OBC category to get admission to IISER with 50 marks. Even the reserved category students have less chance in the later counelling round for admission. To secure admission, students must score above 150 marks.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered a week ago

IISER exam is considered of moderate difficulty level. Majority of students finds Physics, and Mathematics challenging. PCM students may find biology tough while PCB students might find Mathematics tough. However, the difficulty level of IISER compared to JEE Main and Advanced is moderate to easy.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 2 weeks ago

The last date to apply for IISER 2026 is April 13, 2026. IAT application form will be available on the website, iiseradmission.in. 

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 3 weeks ago

IISER 2026 application is available from March 5 to April 13. Eligible candidates can fill the application form online at iiseradmission.in. The process to fill the application form is registration, form filling, and payment of fees.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 3 weeks ago

IISER Berhampur released the application form for IISER 2026 on March 5, 2026. The registration link is updated on the website, iiseradmission.in.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 3 weeks ago

IISER 2026 application fee is updated online. The application fee for IISER 2026 is Rs. 2000 (General, EWS, OBC, and OBC-NCL). For other categories, the fee is Rs. 1000.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 3 weeks ago

The official website to check the result of IISER 2026 is iiseradmission.in. Students have to provide the required credentials to check the exam result.

V

Vikash Kumar Vishwakarma

Contributor-Level 10

Answered 3 weeks ago

There are 2343 seats, including supernumerary seats for BS-MS / BS / B.Tech. programmes.

BS-MS programme seat matrix

IISERTotal Seats
IISER Berhampur300
IISER Bhopal300
IISER Kolkata280
IISER Kolkata (BS-MS in Computational and Data Sciences)30
IISER Pune288
IISER Mohali275
IISER Thiruvananthapuram320
IISER Tirupati250

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Vikash Kumar Vishwakarma

Contributor-Level 10