GPAT Syllabus 2026: Download PDF, Check Subjects & Topic wise Syllabus

Graduate Pharmacy Aptitude Test 2026 ( GPAT )

Rupali Pruthi
Updated on Apr 13, 2026 19:51 IST

By Rupali Pruthi, Deputy Manager - Editorial

GPAT Syllabus 2026: The NBEMS conducts the GPAT exam based on the curriculum of the BPharma course. The NBEMS GPAT 2026 syllabus covers Pharmacy subjects like Pharmaceutics, Pharmacognosy, Pharmacology, Pharmaceutical Chemistry and others. Candidates must go through the GPAT syllabus PDF given on this page to prepare for the exam. Candidates should first gain a clear understanding of the syllabus and then move towards practice and revision. Check the detailed syllabus on this page below along with the subject-wise marks distribution. The GPAT 2026 exam was held on March 7, 2026. 

Table of contents
  • GPAT Syllabus 2026: PDF Download
  • GPAT Syllabus 2026: Subject-Wise
  • GPAT Marking Scheme 2026
  • GPAT Exam Pattern 2026
  • FAQs on GPAT 2026 Syllabus
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GPAT Syllabus 2026: PDF Download

As per the GPAT 2026 information bulletin, the exam syllabus is based on the BPharm course. For the ease of candidates, we have shared the GPAT syllabus PDF, containing the topics from which questions are asked in exam-

GPAT Syllabus PDF

Also Read: GPAT Marks vs Rank 2026

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GPAT Syllabus 2026: Subject-Wise

The GPAT syllabus 2026 comprises nineteen subjects. The subjects and topics of the GPAT exam are the ones taught during the four-year-long BPharma programme. Candidates can check the GPAT 2026 syllabus below.

GPAT Physical Chemistry Syllabus

Here are some important topics from the physical chemistry syllabus of GPAT: 

GPAT Topics

GPAT Sub Topics

Composition & physical states of matter

Intermolecular forces & their impact on the state of the matter. Various physical properties of matter, dipole moment, dielectric constant, Van Der Waal's equation & critical phenomenon, liquefaction of gases, and aerosols.

Colligative Properties

The liquid state, vapor pressure, ideal & real solutions. Raoult's law, the elevation of boiling point, depression of freezing point, osmotic pressure, and determination of molecular weight based on colligative properties.

Thermodynamics

First, second & third laws of thermodynamics, Thermochemical laws, isothermic & adiabatic processes, reversible processes, work of expansion, heat content, enthalpy, and heat capacity. Gibb's & Helmholtz equation & chemical potential.

Solutions

Solubility, factors affecting solubility, solubility curves. Types of solutions, the effect of co-solvency, pH & other factors on solubility. Solubility of gases in liquids, liquids in liquids, & solids in liquids, critical solution temperature, the law of partitioning & its applications. Solute-solvent interactions. Expression of the concentration of pharmaceutical solutions & calculations. Molarity, molality, mole fraction & percentage expressions.

Electrochemistry

Properties of electrolyte solutions, electrolysis. Faraday's law of electrolysis, electron transport, electrical cell, single electrode potential, concentration cells, half-cells & half-cell potential, types of half cells, sign convention, Nernst equation, salt bridge, electromotive series, standard potential, SHE. Measuring the relative voltage of half cells, Calculation of standard potential. Reference & indicator electrodes. Standard oxidation-reduction potential.

Ionic equilibrium

Theory of conductivity, equivalent conductance, mobility of ions, specific conductance. 8. Kinetics Order of reactions, derivation & internal form of rate laws, molarities of reaction, derivation of rate constants.

Also Read: GPAT Question Papers PDFs

GPAT Physical Pharmacy Syllabus

Some crucial topics from the GPAT exam Physical pharmacy syllabus are: 

GPAT Topics

GPAT Sub Topics

Matter, properties of matter

States of matter, change in the state of matter, latent heat and vapor pressure, sublimation critical point, eutectic mixtures, gases, aerosols- inhalers, relative humidity, liquid complexes, liquid crystals, glasses state, solid crystalline and amorphous polymorphism.

Micromeritics and powder rheology

Particle size and distribution, an average particle size number and weight distribution, particle number, methods of determining particle size and volume, optical microscopy, sieving, sedimentation, determining surface areas, permeability, adsorption, derived properties of powders, porosity, packing arrangement densities, bulkiness, and flow properties.

Surface and interfacial phenomenon

Liquid interface, surface and interfacial tensions, surface free energy, measurement of surface and interfacial tension, spreading coefficient, adsorption and liquid interfaces, surface active agents, HLB classification, solubilization, detergency, absorption at solid interfaces, solid gas and solid-liquid interfaces, complex films, electrical properties of interfaces.

Viscosity and rheology

Newtonian systems, law of flow, kinematics viscosity, effect of temperature, non-Newtonian systems, pseudoplastics, dilatant, plastic, thixotropy in formulations, determination of viscosity and thixotropy by capillary, falling ball, rotational viscometer, application of theology in pharmacy

Dispersion systems

Colloidal dispersions: Definition, types, properties of colloids, protective colloids, application of colloids in pharmacy, Suspensions and emulsions: Interfacial properties of suspended particles settling in suspension, theory of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters, wetting of particles, significance of electrical properties in dispersions, controlled flocculation, flocculation in structured vehicles, rheological considerations, emulsions: types, theories, physical stability.

Also Read: GPAT Cutoff 2026

GPAT Organic Chemistry Syllabus

Important topics from the organic chemistry NBE GPAT syllabus 2026 are mentioned below: 

GPAT Topics

GPAT Sub Topics

General principles

A brief review of the classification & sources of organic compounds, Sp3, Sp2, Sp hybridization, sigma & pi- bonds, bond lengths, bond angles & bond energies along with their significance in reactions should be carried out. An overview of bond polarization, hydrogen bonds, inductive effects, resonance, and hyperconjugation be taken. Concepts of homolytic & heterolytic bond fission, acidity & basicity with different theories should be covered briefly. Ease of formation & order of stabilities of electron-deficient & electron-rich species along with the reasons for the same should be covered. Relationships between energy content, stability, reactivity & their importance in chemical reactions should be covered. Calculations for determining empirical & molecular formulas should be covered.

Protection & deprotection of groups

Introduction to protection & deprotection of functional groups. Two examples each for amino, hydroxyl, & carbonyl groups. The significance of these in syntheses should be explained in  NBEMS GPAT 2026 syllabus PDF.

Aromaticity & chemistry of aromatic compounds

Concept of aromaticity, Huckel's rule & its use in determining the aromatic/non-aromatic character of a compound. A brief coverage of the structure of benzene. Detailed coverage of electrophilic & nucleophilic aromatic substitution reactions. Reactivity & orientation in these reactions. Reactivity & orientation in mono- & disubstituted benzenes. Benzyne mechanism.

Polycyclic aromatic hydrocarbons

Syntheses & reactions with mechanisms of bi & tricyclic fused carbocyclic rings like naphthalene, anthracene, & phenanthrene.

Heterocyclic Chemistry

IUPAC Nomenclature of heterocyclic rings [3-10 membered] containing O, S, & N atoms. The nomenclature of above rings containing mono-, di-, & multiple [same or different] heteroatoms should also be covered. Nomenclature of 2 & 3 fused rings containing mono -, di -, & multiple heteroatoms [same or different] should also be covered. Syntheses & reactions of three to six-membered rings in detail. Syntheses of five & six-membered rings containing mono- or any diheteroatoms [O, S, & N]. Syntheses of quinoline, isoquinoline, benzoxazole, benzothiazole, & benzimidazole, benzotriazole, and benzothiazole.

Bridged Rings

Bridged ring systems & their nomenclature.C8, C9, C11 bridged bicyclic alkanes. Chemistry of hexamine, morphan, biperiden, amantadine, diazabicyclo[2.2.2] octane

Carbohydrates

Carbohydrates. Definition & classification. D & L nomenclature in sugars. Different ways of drawing / representing a sugar molecule [including cyclic Structure], interconversion of these representations. Anomers & epimers. Mutarotation. Reactions of glucose. Chain extension & chain reduction of a sugar.

Amino acids & proteins

 Definition & classification. D & L Amino acids, natural, essential, & nonessential amino acids. Denaturation, Strecker, and Gabriel phthalimide methods for the preparation of amino acids. Peptide bond & its formation. Two protective groups each, for -NH2 & -COOH functionalities during protein synthesis. Sequencing of a protein by chemical & enzymatic methods.

GPAT Pharmaceutical Chemistry Syllabus

Read the given topics below to score a high percentile in the Pharmaceutical Chemistry subject: 

GPAT Topics

GPAT Sub Topics

Pharmaceutical Inorganic Chemistry

  • Pharmaceutical Impurities: Impurities in pharmaceutical substances, sources, types & effects of impurities. Limit tests for heavy metals like lead, iron, arsenic, and mercury & for chloride & sulphate as per Indian Pharmacopoeia [I. P.].

  • Monographs: Monograph & its importance, various tests included in monographs as per I. P. A study of the following compounds concerning their methods of preparation, assay, & pharmaceutical uses of sodium citrate, calcium carbonate, copper sulphate, light & heavy kaolin, ammonium chloride & ferrous gluconate.
  • Isotopes: Isotopes- stable & radioactive, mode & rate of decay. Types & measurement of radioactivity. Radiopharmaceuticals & their diagnostic & therapeutic applications in pharmacy & medicine such as 125I, 32P, 51Cr, 60Co, 59Fe, 99Tc-M. Radiocontrast media, use of BaSO4 in medicine.
  • Dentifrices, desensitizing agents, & anticaries agents

Medicinal Chemistry

Therapeutic classes of drugs, Various classes of therapeutic agents

Pharmacy Profession & Introduction to Pharmaceuticals

Pharmacy as a career, evaluation of Pharmacy, earlier period middle to modern ages. Definition, importance of pharmaceuticals, areas concerned, scope of Pharmaceutics, history and development of the profession of Pharmacy and Pharmaceutical industry in India. A brief review of present Indian Pharma. Industry in global perspective.

Allopathic dosage

Merits/demerits, importance, formulation development - vehicles/excipients with examples for the dosage form: liquid dosage form: monophasic liquid dosage form. Aromatic waters, syrup, elixir, linctus, lotion, liniment, glycerites, solutions, spirits, ENT preparations, mixtures, paints, mouthwash.

Also Read: GPAT 2026 Toppers List (Out)

GPAT Pharmacology Syllabus

The Pharmacology topics can be revised using the topics given below: 

GPAT Topics

GPAT Sub Topics

General Pharmacology

Introduction to Pharmacology- Definition, scope and source of drugs, dosage forms and routes of drug administration. Pharmacodynamics-Mechanism of drug action, Receptors, classification and drug-receptor interactions, combined effects of drugs, factors modifying drug actions. Pharmacokinetics-Mechanism and principle of absorption, distribution, metabolism and excretion of drugs. Principles of basic and clinical pharmacokinetics. Pharmacogenetics. Adverse drug reactions. Discovery and development of new drugs-Preclinical and clinical studies.

Pharmacology of peripheral nervous system Parasympathomimetics, Parasympatholytics, Sympathomimetics, Sympatholytics, Ganglionic stimulants and blockers. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral). Local anesthetic agents. Drugs used in Myasthenia Gravis.
Pharmacology of cardiovascular system Introduction of hemodynamics and Electrophysiology of heart. Page 18 of 54 Anti-hypertensive drugs, Anti-anginal agents, Anti-arrhythmic drugs. Drugs used in congestive heart failure. Anti-hyperlipidemic drugs. Drugs used in the therapy of shock. Haematinics, anticoagulants and haemostatic agents. Fibrinolytics and antiplatelet drugs. Blood and plasma volume expanders.
Chemotherapy General principles of chemotherapy. Sulphonamides and co-trimoxazole. Antibiotics- Penicillins, cephalosporins, chloramphenicol, Macrolides, quinolones and fluoroquinolons,. Tetracyclines. Aminoglycosides and miscellaneous antibiotics. Chemotherapy of tuberculosis, leprosy, fungal diseases, viral diseases, AIDS, protozoal diseases, worm infections, urinary tract infections and sexually transmitted diseases. Chemotherapy of malignancy.
Autacoids and their Antagonists Histamine, 5-HT and their agonsists and antagonists. Prostaglandins, thromboxanes and leukotrienes. pentagastrin, cholecystokinin, angiotensin, bradykinin and substance P.,Analgesic, anti-pyretic, anti-inflammatory and anti-gout drugs.

GPAT Syllabus 2026 PDF: Pharmacognosy

Relevant topics from Pharmacognosy syllabus expected in the GPAT entrance exam are: 

GPAT Topics

GPAT Sub Topics

Introductory Pharmacognosy

Historical development, modern concept and scope of Pharmacognosy. The significance of Pharmacognosy in various systems of medicine practiced in India viz: Ayurveda, Unani, Homeopathic and Siddha.

Classification of crude drugs

Based on alphabetical, morphological, pharmacological, chemical, taxonomical and chemotaxonomic methods: organized and unorganized drugs: official and unofficial drugs. Plants, animals and minerals: marine products: plant tissue culture.

Techniques in microscopy

Details of mountants, clearing agents, and chemomicroscopic (microchemical) reagents.

Introduction to phytoconstituents

Definition, classification, chemical tests and pharmaceutical importance of: carbohydrates and their derivatives, fats and proteins, alkaloids, glycosides, flavonoids, steroids, saponins, tannins, resins, lipids and volatile oils

Introduction to phytoconstituents

Definition, classification, chemical tests and pharmaceutical importance of: carbohydrates and their derivatives, fats and proteins, alkaloids, glycosides, flavonoids, steroids, saponins, tannins, resins, lipids and volatile oils.

GPAT Biochemistry Syllabus

In the Biochemistry subject generally the given below topics are asked in the exam to evaluate the aptitude of candidates:  

GPAT Topics

GPAT Sub Topics

Cell Revision of ultrastructure of the cell, functions of various cellular constituents. Applications of biochemical principles to the pharmacy.
Carbohydrates Types of carbohydrates, their functions, digestion, & absorption. Aerobic & anaerobic oxidation with energetics. Glycogenesis, glycogenolysis, & gluconeogenesis. Hexose monophosphate shunt [HMP shunt]. Diseases associated with carbohydrate metabolism.
Proteins Different types of proteins. Their functions, digestion & absorption. Denaturation & its effect on biological activity. Renaturation of proteins. Urea formation, urea cycle, creatinine formation. Transamination & deamination. Proteins as enzymes.
Lipids

Different types of lipids. Their functions, digestion, absorption & metabolism. (Beta-Oxidation of fatty acids with energetics. Biosynthesis of cholesterol [from acetate], adrenocorticoids, androgens, progesterone, estrogens, & bile acids / salts. Ketone bodies, their formation & biochemical significance. Diseases associated with lipid metabolism.

Vitamins Definition. Classification, structures [except B12] biochemical role, sources, daily requirements, & deficiency symptoms. Vitamins as co-factors in biochemical reactions.

Biological oxidations & reductions

Oxidation-reduction systems in the body their role. Oxidative phosphorylation & Electron transport chain. Cytochromes & inhibitors of the same.

Enzymes

Classification & their various roles. Enzyme co-factors. Enzyme kinetics. Michaelis-Menton equation along with its transformations. Double reciprocal plot. Factors affecting enzyme action. Enzyme inhibition, competitive & non-competitive, & kinetics.

GPAT Biotechnology Syllabus 

Here are some important Biotechnology related topics which are often seen in GPAT exam: 

GPAT Topics

GPAT Sub Topics

Plant Cell and Tissue Culture 

Cell and tissue culture, Processes and applications

Animal Cell Culture

Introduction to animal cell culture, medium used in ATC. Use of FCS, primary culture, secondary culture, cell line. Cloning: concept and application with technical hurdles. Transgenic animals as a source of food, organs and tissues, concept of xeno transplant.

Fermentation Technology and Industrial Microbiology

Fermentation as a biochemical process, types of fermentation.2. Fermenter - working and construction, accessory components, modification.3. Fermentation monitoring and in situ recovery of products.
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GPAT Marking Scheme 2026

Applicants who want to appear in the exam can check the GPAT 2026 marking scheme, which will help them to prepare and make a strategy to qualify for the exam with good marks.

GPAT Exam Pattern Highlights

Total number of Questions

125

Marks for each correct answer

4

Marks for each incorrect answer

-1

Marks for unattempted questions 0

Total marks

500

Negative marking

Yes, Applicable

The nature of questions asked in the GPAT exam are objective, and the exam is conducted in computer-based test mode.

Predict your college based on GPAT 2026 Score & Rank - GPAT College Predictor
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GPAT Exam Pattern 2026

Students who want to appear in exam must know GPAT exam pattern. It will help them to strategize their plan to qualify exam. The below table brings an overview of the GPAT pattern.

Parameters

Details

Duration of the examination

3 hours (180 minutes)

Total questions

125

Total marks

500

Marks for correct answer

+4

Marks for incorrect answer

-1

Negative marking

Yes

Questions type

Objective types

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FAQs on GPAT 2026 Syllabus

Read Frequently Asked Questions (FAQs) Regarding GPAT Syllabus here:

Q:   How many subjects are covered under GPAT syllabus?
A: 

The GPAT syllabus generally comprises nineteen subjects. Questions from important topics of these subjects are generally seen in the exam as per the previous year trend. There are 5 five sections in GPAT 2026 exam namely Pharmaceutical Chemistry & Allied Subjects, Pharmaceutics & Allied Subjects, Pharmacognosy & Allied Subjects, Pharmacology & Allied Subjects, and other subjects. All the 19 topics are bifurcated among these 5 sections in the exam. There will be objective-type questions in the entrance exam.

Q:   Can I download GPAT syllabus in Hindi?
A: 

Since NBEMS does not release GPAT syllabus PDF hence students can't get it. The GPAT 2026 syllabus is released in English language at the official website of The Bachelor of Pharmacy (B. Pharm.) Course Regulations. Therefore, the entire syllabus provided to the candidates is in English language only. Candidates preparing for the M.Pharma entrance exam are advised to prepare for the exam in English medium only. The entrance exam is also conducted in English medium and not in Hindi medium.

Q:   What should I prepare under Biopharmaceutics and Pharmacokinetics subjects for GPAT?
A: 

Candidates can prepare topics such as Bio-pharmaceutics, Bio-availability and bio-equivalence, Biopharmaceutical Statistics under Biopharmaceutics and Pharmacokinetics subjects for GPAT 2026. Other topics in Pharmacodynamics include Mechanism of drug action, Receptors, classification and drug-receptor interactions, combined effects of drugs, factors modifying drug actions, principle of absorption, distribution, metabolism and excretion of drugs. Principles of basic and clinical pharmacokinetics.

Q:   Can I get a refund if I decide not to appear for the GPAT exam after registration?
A: 

No, Applicants who are planning to appear in GPAT exam must note that there will be no refund if the candidates who completed the registration and pay the application fees. Hence one must be very careful before filling the form and submit the fees while appearing in the exam. 

Q:   Is it compulsory to appear for GPAT exam to get admission for MPharma?
A: 
No, in order to pursue M.Pharma you don't have to clear a GPAT exam. There are many private colleges in India like Amity University, Jamia Hamdard Manipal University, etc. Which offer all those an opportunity to pursue M.Pharma without qualifying a GPAT test. They take students under management quota without any prior entrance tests. In case you clear this exam you would be able to get admission in some of the best colleges in India offering M.Pharma. Aditionally you will be getting a stipend for 12400 INR along with an impressive build for your resume for much better future opportunities.
Q:   What should I prepare from Physical Chemistry for the GPAT exam?
A: 

Questions from important topics such as Composition & physical States of Matter Colligative Properties, Thermodynamics Refractive index, Ionic equilibrium, Solutions, Electrochemistry are seen in the exam. Candidates are advised to prepare these topics thoroughly. The GPAT Organic Chemistry Syllabus comprise of topics such as Different classes of compounds, Protection & deprotection of groups, Aromaticity & Chemistry of aromatic compounds, Different aromatic classes of compounds, Polycyclic aromatic hydrocarbons, Carbonyl Chemistry etc.

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